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Fosamprenavir calcium

CAS No. 226700-81-8

Fosamprenavir calcium( GW-433908 | GW-433908G )

Catalog No. M13619 CAS No. 226700-81-8

A phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 329 Get Quote
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Biological Information

  • Product Name
    Fosamprenavir calcium
  • Note
    Research use only, not for human use.
  • Brief Description
    A phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.
  • Description
    A phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.HIV Infection Approved.
  • In Vitro
    The calcium salt of the prodrug, Fosamprenavir Calcium Salt (GW433908G), is selected for further investigation, as it appears to offer the greatest potential for the development of new drug formulations.
  • In Vivo
    ——
  • Synonyms
    GW-433908 | GW-433908G
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    Infection
  • Indication
    HIV Infection

Chemical Information

  • CAS Number
    226700-81-8
  • Formula Weight
    623.6689
  • Molecular Formula
    C25H34CaN3O9PS
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: 0.25 mg/mL (Need ultrasonic and warming); DMSO: 1.8 mg/mL
  • SMILES
    CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2]
  • Chemical Name
    Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-, (3S)-tetrahydro-3-furanyl ester, calcium salt (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Falcoz C, et al. J Clin Pharmacol. 2002 Aug;42(8):887-98. 2. Furfine ES, et al. Antimicrob Agents Chemother. 2004 Mar;48(3):791-8. 3. Wire MB, et al. AIDS. 2004 Apr 9;18(6):897-907.
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