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Fosamprenavir calcium
CAS No. 226700-81-8
Fosamprenavir calcium( GW-433908 | GW-433908G )
Catalog No. M13619 CAS No. 226700-81-8
A phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 125 | Get Quote |
|
| 10MG | 205 | Get Quote |
|
| 25MG | 329 | Get Quote |
|
| 50MG | 446 | Get Quote |
|
| 100MG | 647 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFosamprenavir calcium
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NoteResearch use only, not for human use.
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Brief DescriptionA phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.
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DescriptionA phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.HIV Infection Approved.
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In VitroThe calcium salt of the prodrug, Fosamprenavir Calcium Salt (GW433908G), is selected for further investigation, as it appears to offer the greatest potential for the development of new drug formulations.
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In Vivo——
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SynonymsGW-433908 | GW-433908G
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number226700-81-8
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Formula Weight623.6689
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Molecular FormulaC25H34CaN3O9PS
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Purity>98% (HPLC)
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SolubilityH2O: 0.25 mg/mL (Need ultrasonic and warming); DMSO: 1.8 mg/mL
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SMILESCC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2]
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Chemical NameCarbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-, (3S)-tetrahydro-3-furanyl ester, calcium salt (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Falcoz C, et al. J Clin Pharmacol. 2002 Aug;42(8):887-98.
2. Furfine ES, et al. Antimicrob Agents Chemother. 2004 Mar;48(3):791-8.
3. Wire MB, et al. AIDS. 2004 Apr 9;18(6):897-907.
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